Capto resin7/22/2023 Both resins can be introduced for the industrial purification of the r-HBsAg, attending to process specifications. The dynamic adsorption capacity of Cellufine MAX Q-hv resin (1.5 mg r-HBsAg/mL of resin) was higher than that for Capto Q (0.9 mg r-HBsAg/mL of resin), with more than 40 % of the chromatographic bed of both resins used is inefficiently. The maximum adsorption capacities of both resins were similar, with values between 1.5 and 1.8 mg of r-HBsAg/mL of gel. The Capto Q resin had an association constant 3.89 times higher than the Cellufine MAX Q-hv resin. Cellufine MAX Q-hv and Capto Q resins were assessed kinetically and thermodynamically, and their the adsorption behavior of r-HBsAg were predicted by Langmuir isotherms with a good adjustment (R2 > 90 %). This value was statistically different (p 0.05) to that of TMAE anion resin (Merck), currently in use for the industrial production process of the HeberBiovac HB® vaccine. The highest r-HBsAg recoveries were obtained with Capto Q resin (87.16 ± 1.34 %). In this work, the anion exchange chromatographic resins Cellufine MAX Q-hv from JNC Corporation (Japan) and Capto Q from GE Healthcare Life Science (USA) were evaluated for the purification process of the recombinant hepatitis B surface antigen (r-HBsAg), as active pharmaceutical ingredient. High-resolution intermediate purification and polishing resin based on the well-established Capto platform with traditional ligands. Anion exchange chromatography, adsorption isotherms, breakthrough curves, r-HBsAg.Ī thermodynamic and kinetic understanding of chromatographic separation is required for the design of the chromatographic process’ operating system.
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Jak and daxter ps2 framerate7/22/2023 ![]() The ports have always been of variable quality – often full of pop-in and framerate hitches – but never anything particularly noticeable, and they’ve always managed to look beautiful thanks to some great modelling and environmental design. ![]() ![]() It seems the same thing happened to Accel World, and as such we’re left with very sloppy ports of the final two Sword Art Online games on the handheld.Ītelier has pretty much been Vita’s most prominent series alongside Hyperdimension Neptunia, with eight entries released over the course of five years. With Hollow Realization, the main version was developed for PS4 and then it was ported to Vita – which causes a lot more difficulties due to the power gap between the two consoles than developing for Vita and porting up to PS4. See, Hollow Fragment was based on a PSP game – meaning with the Vita’s increased power, it ran pretty well while Lost Song was developed first for Vita then ported to PS3. The reason for this seems fairly simple – in that the Vita stopped being the lead version for development after Lost Song. This was particularly disappointing given what the developers had previously achieved on the handheld, even with their last Sword Art Online game. Despite being based on the Lost Song engine to the point vast amounts of content were copied across, the game had taken a serious graphical hit with models looking pixelated and pop-in being extremely evident and the framerate was suddenly all over the place. Things had gotten even worse by 2017’s Accel World vs. In addition, the framerate slowed to a crawl during boss battles something that was only slightly improved by patches. The game – also available on PS4 and developed by Aquria – had taken a serious graphical downgrade in their porting process, removing plenty of environmental objects and effects as covered in Havian’s video. Yet somehow in 2016 with the release of Hollow Realization, the series suddenly took a massive downturn in terms of quality. They often took full advantage of the console’s capabilities, with graphically impressive titles like Macross Delta Scramble – and Lost Song was very much in this vein, with big open areas that actually ran pretty well on Vita – solidifying them as one of the handheld’s best developers. This was followed up in 2015 with Lost Song from developers Artdink, who also had a long history on the handheld ranging from Gundam SEED Battle Destiny in 2012 right through to Neo Atlas 1469 last year. The game had some slowdown in its main town area, but overall the title ran well – mainly due to the fact it was a PSP up-port. Developed by Aquria, the game was impressive at the time, packing in a tonne of content into its pseudo-MMO setting while still maintaining the feel of the anime. The Sword Art Online series has a fairly long history on Vita, starting in 2014 with the release of Hollow Fragment, an expanded release of the 2013 PSP title Infinity Moment. ![]() Sword Art Online: Millennium Twilight (and Sword Art Online: Hollow Realization) In this article, I aim to examine these ports – what was disappointing about them (and why they should have been better than they were), as well as possible explanations on why they turned out the way they did alongside a conclusion on how well the Vita did as a machine capable of handling console ports during its lifespan.Īccel World vs. Despite being the strongest handheld console released in 2011 and being more than capable of handling ports of PS2 PS3 and even PS4 titles when the developers put the effort in, not every company was willing to take the time to ensure the Vita version turned out well – and as such we have a number of great games that remain hugely disappointing on the handheld due to the way they run. I recently wrote an article looking at Vita’s 10 most technically impressive games, that I always intended to be a two-part series also looking at Vita’s 10 most technically disappointing games. Goodsync for mac vs7/22/2023 The enterprise version of GoodSync offers a centralized management server to remotely configure and monitor jobs inside the enterprise. The backup software is used to copy changes in directories from one machine to another. The file synchronization job detects file changes in directories and synchronizes the changes between two machines. GoodSync, and programs similar to GoodSync, perform two primary job functions : file synchronization and file backup. GoodSync does a solid job of transferring data and synchronizing files between two computers. GoodSync, by Siber Systems, is a well-known file synchronization and backup software program built on a standard client-server architecture. Early demonstrations of learning a foreign language are promising as is the student being able to ask the ”why” of how Python is structured, not just the ”get it done” without understanding that online education often creates.Finally, having an eye toward inclusivity for everyone of any gender, race or social status is something that needs to be baked in.GoodSync Alternative: Considerations and Overview So, this means that there is a possibility that there could be a commercial incentive which is much better than constantly asking for charitable dollars.The new LLMs promise interactivity and individualized instruction that was impossible before. Both Devindra and I are the beneficiaries of that thinking and we are forever grateful to our parents for their sacrifice. And with advances like 4-bit quantization, there is the possibility they can even run on modern smartphones.The experience in China and in India is that parents will save inordinately to give their children a better life than theirs. ![]() While these large language models today mainly work in the cloud and require high-speed internet connectivity, the promise is that smaller models that are more specialized have already been ported to MacBook Pro M1 and other laptops. Then the key flags are a for copy all, -P for show progress and -n to do a dry run to see waht it will do, so the generic command looks like # Test to see what the command will doĪ conversation with Devindra on the possibilities of ChatGPT and other Large Language Models for education in India and other Middle and Low-Income Countries. First off, the source should also have a trailing slash so it does the copy at the right level. The Digital Ocean tutorial is good and remind me of all the key things. This time I've learned my lesson and am using the latest rsync courtesy of brew install rsync and things seem to work better. And it is very old to go through with finder and check things.Goodsync for some reason has gotten really slow.Bad copies, so it would be nice to have some checksums. And I use Synology Backup to also back it up into Google Drive. ![]() Then from the NAS, I use Goodsync which has a decent synchronizer as well to my backup drive array. For a while I used the base rsync that's part of every version of MacOS, but about four years ago, it started not to sync properly. ![]() I do keep a copy in iCloud Photos, which remarkably is dealing with 54K photos and 2K videos decently well (except for Mac Photos which seems to hang alot and not sync, but that's another post).īut for backups, when I'm on the road, I have my laptop and then every so often with manually copy files down to an SSD drive.īut when I get home, I often forget what is what, so then you have to go through manually and figure it out. The biggest problems are my personal photos. Jackson over here with my homeboy You know what I'm saying I'm just helpin 'em out on this microphone It goes hippa to the hoppa and it just don't stoppa I'm dressed in all black with my man K. Roper Home of the (NEW) generation, we got the torch Let me call into U-D Dustin to bust 'em off Blown Celeb and resurrecting the dead with three day block Posse cut resurrection instead, so pass the ROCK! I'm about to pop the clip in as I stop the opposition You gotta cop a listen when I'm knockin like a piston I spit arsenic so I'm hard to miss You're in a DAZE cause I BLAZE like an arsonist I come up in the house like a thief in the night And electrify a crowd like keys on a kite (STAY CALM!) Before I drop the napalm Find yourself caught in a dangerous liaison Lay it on thick, brick by brick, lickety split Rhymes are fat like Jiminy Glick You want beef, here's a hickory stick, I shoot the gift You won't know it till it's over like a mystery flick To put it blunt, I pack a punch like a school lunch Got no time for punks, they take lumps So PLEASE stop bugging for my honeycombs Or I'll hit you in the funny bone (OWW!) Man, I wanna know WHAT YOU GOT! Load it up and HIT THAT SPOT! Grab the mic and SHOOT YOUR SHOT! Come on, you gotta SHOOT YOUR SHOT! (Yeah, yeah) We wanna know WHAT YOU GOT! (Yeah, yeah) Load it up and HIT THAT SPOT! (Yeah, yeah) Grab your mic and SHOOT YOUR SHOT! Andy's the name, takin aim like Calamity Jane In a rap's last stand I'm the man who remains When I claim to pack heat (uh-huh), know my ammunition Is my flow and rhythm SO I'm armed to the teeth My lungs are gun powder, throat cold and narrow So when I open my mouth you're looking down the barrel Of an emcee sniper, eye in the scope Reigning down rounds of rhyme, fire, and smoke (BOOM!) Lighting strikes twice from my mic device Cause when I write it's like guns in knife fights There's no competition so I don't listen You think you're dope here's a penny, go wishin I shoot to kill, better know the odds Or wind up on boot hill, man get out of dodge (U-D!) plus Thes One and Double K We all just laugh when your record is played Ain't nothing funny, what y'all laughin at? Yeah, it's K. ![]() Jax, he rolls up the weed like haystacks To bath tub down on you scrubs like Ajax You're too fruity to rip the rooty tooty with your loofah New booty ladies too lazy to raise the roof up The plug desenchufa, could the crew get any doper Man, we own this, live under the stairs like Mr. ![]() Man, I wanna know WHAT YOU GOT! Load it up and HIT THAT SPOT! Grab the mic and SHOOT YOUR SHOT! Hey yo, P-U-T-S and U-D, you be truly blessed Rap panelist, Thes handle this like an analyst (YES!) yes y'all the Einstein rhythm and rhyme Combines like red wine and Tylenol (OOOOH!) Shit, the grown relaxing in the field But don't sleep, P count green, not sheep With K. Spideroak vs backblaze7/21/2023 ![]() ![]() However, there are certain shortcomings of this service too for example, it cannot back up the system completely, like system files, etc. It can also help in locating a lost or stolen PC. It offers to send hard drive backup or DVDs for $189 and $99 respectively, which is much faster and convenient than online restoration and in this aspect Backblaze is much more reasonable than Carbonite. These services vary in terms of price ranges and the set of features that they provide.īackblaze is the online backup service that offers unlimited storage space for personal files quite inexpensively. The top 5 widely known online backup services are Backblaze, Carbonite, Crashplan, Mozy and Norton Online Backup. There are often limitations put up by such service providers on the file types that can be uploaded- usually personal files are the ones that can be archived not system files. As aforementioned, the initial backup up process is painstakingly long sometimes taking days to upload data, depending on the amount of data and the bandwidth of user's connection. Now, backing up your data imperative for users who work with records or information they have accumulated over time or is otherwise irreplaceable, but it does come with some low points. There are about 4 dozen companies offering online backup with many features like other than restoring files to the original PC several allow to restore the files on a smart phone, tablet or even share them with an email contact. The idea works because of the utility it has to offer as no extra hardware or drives are needed to back up the most critical data, only the initial set up is long but after that archiving and updating can run really fast and automatically. So now the question arises as to what is an online backup service? And why is there even a need for one? Online Backup Services are modern age's popular response to data nightmares they help maintain archives of our key data on the particular company's servers in the cloud. Why do you need an online data backup service ![]() Instead of the convention of storing backup in external hard drives, another method that has caught the public eye is that of using online backup services. While such a meager amount of users take regular measures to avoid any data disasters, there is around 1/3rd of the total number of users who never back up their systems. Still, according to over 2 thousand respondents in a Backblaze poll by Harris Interactive, only 7 percent users archive their PCs daily. The point about filing away our data is a similar case, as we know its advantages outweigh the disadvantages clearly and it is among those things that ought to be done. Constrictor ves wolfenstein wiki7/21/2023 ![]() Other examples of sexual dimorphism in the species include males generally having longer tails to contain the hemipenes and also longer pelvic spurs, which are used to grip and stimulate the female during copulation. constrictor reaches, and occasionally tops, the averages given above, as it is one of the relatively large subspecies of Boa constrictor. The size and weight of a boa constrictor depends on subspecies, locale, and the availability of suitable prey. Some specimens of this species can reach or possibly exceed 45 kg (100 lb), although this is not usual. Females, the larger sex, more commonly weigh 10 to 15 kg (22 to 33 lb). The boa constrictor is a heavy-bodied snake, and large specimens can weigh up to 27 kg (60 lb). A report of a boa constrictor growing up to 18.5 ft (5.6 m) was later found to be a misidentified green anaconda. The largest documented non-stretched dry skin is deposited at Zoologische Staatssammlung München (ZSM 4961/2012) and measures 14.6 ft (4.45 m) without head. Females commonly exceed 10 ft (3.0 m), particularly in captivity, where lengths up to 12 ft (3.7 m) or even 14 ft (4.3 m) can be seen. The usual size of mature female boas is between 7 and 10 ft (2.1 and 3.0 m) whereas males are between 6 and 8 ft (1.8 and 2.4 m). Clear sexual dimorphism is seen in the species, with females generally being larger in both length and girth than males. The boa constrictor is a large snake, although it is only modestly sized in comparison to other large snakes, such as the reticulated python, Burmese python, or the occasionally sympatric green anaconda, and can reach lengths from 3 to 13 ft (0.91 to 3.96 m) depending on the locality and the availability of suitable prey. melanogaster Langhammer, 1983: a nomen dubium ĭescription Size and weight Several other subspecies have been described at different times, but currently, these are no longer considered to be valid subspecies by many herpetologists and taxonomists. ![]() ![]() The subspecific name ortonii is in honor of American naturalist James Orton. South America except for the ranges of the other three subspecies Boa imperator, Boa nebulosa, Boa orophias and Boa sigma have all been elevated to full species status. Some appear to be based more on location rather than on biological differences. Several subspecies of Boa constrictor have been described in the past, but many of these are poorly differentiated, and further research may redefine many of them. Other common names include chij-chan ( Mayan), jiboia ( Latin American), and macajuel ( Trinidadian). Within the exotic pet trade, it is also known as a "BCC", an abbreviation of its scientific name, to distinguish it from other boa species, such as Boa imperator or "BCI." Īll subspecies are referred to as "boa constrictors", and are part of a diverse group of New World boas referred to as "red-tailed" boas, comprising the species Boa constrictor and Boa imperator. Only one other vertebrate animal shares this trait, the theropod dinosaur Tyrannosaurus rex. Though all boids are constrictors, only this species is properly referred to as the "boa constrictor" - an instance of an animal having the same English common name and scientific binomial. This article focuses on the species Boa constrictor as a whole, and on the nominate subspecies B. A staple of private collections and public displays, its color pattern is highly variable yet distinctive. The species is native to tropical South America. The boa constrictor is a member of the family Boidae. ![]() The boa constrictor (scientific name also Boa constrictor), also known as the red-tailed boa, is a species of large, non-venomous, heavy-bodied snake that is frequently kept and bred in captivity. Djay pro vs rekordbox7/21/2023 ![]() This makes it difficult to look at it on macro search graphs, but you still can get a good idea. Is it “Rekordbox DJ”, “Rekordbox’s Performance Pack”, or just “Rekordbox”? An issue here is that Rekordbox DJ suffers from a serious branding problem. The youngest entrant into the DJ space is Rekordbox DJ. Here’s the same graph for the last 5 years: Here’s the graph for the most popular DJ software between 2004 and now: These are the two-word phrases that most people use when referring to each platform ( more on Rekordbox’s issues on this front in the next section). This is a tool that allows you to see how often a phrase is searched, and compare it with other terms.įor the graph below, I’ve chosen the most fair name, in quotes, for each DJ software – Traktor Pro, Rekordbox DJ, Serato DJ, and Scratch Live ( for relative context). One of the most fun – albeit not scientifically precise – ways to find out about relative popularity of DJ softwares is to use Google Trends. ![]() Instead, we’ll have to look at data around the topic at hand: What Does Google Say The Most Popular DJ Software Is? The main unknown here is the number of active users – a secret that Serato, Native Instruments, Pioneer, and others all keep closely guarded. But which one is used by the most DJs? We try to find out in this article. Instead of highly specialized tools, there now a handful of options that all have a near-comparable feature set. MIXO’s app is available for download on their website, with both free and subscription options for users to choose from.Digital DJs have a drastically different landscape than they did ten years ago. We suspect that the success of MIXO will depend on its ability to adapt to user needs and deliver continuous improvements/stable support for every new DJ software update (ie: a new update to Rekordbox? It better work as near to launch-day as possible.) The free MIXO download option provides users with access to basic features, while the MIXO:GOLD subscription service, priced at $7/month (€6 or £5) with a 7-day free trial, offers additional features such as bridge tools to import & export your DJ library between Serato, TRAKTOR, Rekordbox, Virtual DJ, and all other DJ platforms. ![]() MIXO also allows DJs to integrate their personal library, cues, loops, and playlists into all popular DJ software from a single account. MIXO’s mobile app enables DJs to manage their library from anywhere, and the platform connects with cloud storage providers like Dropbox and Google Drive for seamless library syncing and automatic online backups. For a long time, every DJ software app has been incentivized to allow iTunes/Music app integration because it’s such a heavily-used tool – but now the impetus will be on MIXO to keep their integrations up to date. Even post-Music app drama, MIXO must prove that its platform can offer a smoother and more efficient, simple experience while seamlessly integrating with multiple DJ software platforms. Replacing iTunes for DJs is no small feat. The platform is compatible with Traktor, Cross DJ, Virtual DJ, Engine Prime, Deckadance, Ultramixer, iTunes, Serato, Mixxx, Rekordbox, and djay, allowing DJs to export their music and retain all custom metadata. In addition to these features, MIXO visually represents album artwork on all synced devices, enhancing the user experience. The platform enables DJs to curate and edit playlists, add, edit, and delete track cue points, and update track metadata, such as star ratings and individual track comments, from their phone. ![]() MIXO allows for offline use, enabling DJs to download some or all of their tracks to their devices and manage their music wherever they are. A significant aspect of Mixo is the mobile/desktop integration, which enables it to work with all DJ software on both phone and laptop. With MIXO, DJs will theoretically be able to edit tracks, update playlists, add cue points, and prepare their music on the go or in the studio, syncing changes to all devices. The platform offers DJ-specific features like waveforms, beat-grid editing, hot cues, loops, and playlist management, aiming to provide DJs with full control over their music organization. Avengers infinity war7/21/2023 ![]() As the Avengers and their allies have continued to protect the world from threats too large for any one hero to handle, a new danger has emerged from the cosmic shadows: Thanos. Two more sequels are in development, entitled Avengers: The Kang Dynasty and Avengers: Secret Wars, both releasing on and May 1, 2026, respectively.Īn unprecedented cinematic journey ten years in the making and spanning the entire Marvel Cinematic Universe, Marvel Studios' " Avengers: Infinity War" brings to the screen the ultimate, deadliest showdown of all time. The fourth film in the series, Avengers: Endgame, was released on April 26, 2019. as Tony Stark/Iron Man, Chris Hemsworth as Thor, Mark Ruffalo as Bruce Banner/Hulk, Chris Evans as Steve Rogers/Captain America, Scarlett Johansson as Natasha Romanoff/Black Widow, Benedict Cumberbatch as Stephen Strange/Doctor Strange, Don Cheadle as James Rhodes/War Machine, Tom Holland as Peter Parker/Spider-Man, Chadwick Boseman as T'Challa/Black Panther, Zoe Saldana as Gamora, Karen Gillan as Nebula, Tom Hiddleston as Loki, Paul Bettany as Vision, Elizabeth Olsen as Wanda Maximoff/Scarlet Witch, Anthony Mackie as Sam Wilson/Falcon, Sebastian Stan as Bucky Barnes/Winter Soldier, Idris Elba as Heimdall, Peter Dinklage as Eitri, Benedict Wong as Wong, Pom Klementieff as Mantis, Dave Bautista as Drax the Destroyer, Vin Diesel as Groot, Bradley Cooper as Rocket Raccoon, with Gwyneth Paltrow as Pepper Potts, Benicio del Toro as Taneleer Tivan/Collector, with Josh Brolin as Thanos, and Chris Pratt as Peter Quill/Star-Lord. ![]() The film is directed by Joe Russo and Anthony Russo and stars Robert Downey, Jr. ![]() It is the nineteenth film in the Marvel Cinematic Universe, and the seventh installment of Phase Three. 2, Spider-Man: Homecoming, Thor: Ragnarok and Black Panther. The film is a sequel to The Avengers, Avengers: Age of Ultron, Captain America: Civil War, Doctor Strange, Guardians of the Galaxy Vol. Or should I say, I am." ― ThanosĪvengers: Infinity War is a 2018 superhero film, based on the Marvel Comics superhero team of the same name. ![]() To feel so desperately that you're right, yet to fail nonetheless. Avengers: Infinity War saw our heroes face defeat on an unprecedented scale, and Avengers: Endgame had to put those pieces back together, which is exactly where the story begins. It was almost three films in one, serving as a powerful meditation on grief, a time-traveling adventure to acquire the stones before Thanos, and culminating in the most ambitious third act the MCU has ever attempted."I know what it's like to lose. However, the fourth Avengers film had a very different job from the third, thanks to Thanos' victory. Far less straightforward than its predecessor, the movie may have been more confusing for some to follow. If the movie truly belonged to any one character, it was the Mad Titan - even if his actual plan wasn't well thought-out.Īvengers: Endgame unfolded quite differently, giving the story a bit more room to breathe and spreading out across multiple timelines. Avengers: Infinity War had a tightly-plotted script that played out logically, but the narrative thread tying everything together was Thanos and his quest to find the Infinity Stones. This was no easy task, with the Guardians of the Galaxy movies being mostly removed from the rest of the MCU, Thor and Hulk being off-world during Thor: Ragnarok, and other characters, like Doctor Strange, having little involvement with the rest of the heroes. While this makes a comparison somewhat difficult, these movies had very daunting missions to pull off, and fans have been divided on which one was more successful. It won't be easy to pick a winner here, but which movie ultimately comes out on top?Īvengers: Infinity War had to merge storylines from multiple franchises and figure out how to get all of the main characters together. RELATED: Every Upcoming Marvel Cinematic Universe Movieĭespite the fact that the two Avengers movies were largely shot side by side and were initially planned as Infinity War, Parts 1 and 2, Avengers: Infinity War and Avengers: Endgame are two distinct films. However, Avengers: Endgame’s job of giving "The Infinity Saga" a satisfying conclusion was arguably an even more difficult ask. Avengers: Infinity War had the unprecedented task of bringing together heroes and storylines from more than twenty films. Avengers: Age of Ultron may have been a misstep for the franchise, but there is no doubt the last two Avengers films righted the ship. The studio’s carefully laid plans panned out and eventually led to an expanded universe beyond what any audience could’ve possibly imagined when these heroes first assembled. Thankfully, the 2012 movie proved Marvel’s reach did not exceed its grasp. The first phase of the MCU included solo films for its main heroes, setting up the ultimate team-up with The Avengers. Google my business support7/21/2023 ![]() Most users who I see on the support forums feel as though their whole business is going to collapse if they do not get support right away. ![]() There can be some issues that are downright frustrating. Getting support for Google My Business (GMB) is not as hard as it sounds. If you do not see anything that can assist you then click next step and you will be presented with a way to contact support via email.įill out the form and Google will then send you an auto-reply. Then you are going to be presented with community articles that may answer your question and also links to official Google My Business Support help documentation. If non of the suggestions apply, click other. To get support simply type in your issue, you will be presented with chips that are suggestions on what your issue may be. The ONLY way to contact support is via the support wizard located here: Previously : As of March 2020 (Due to Covid-19) Live Chat, Phone, and Social support no long are accessible. The ONLY way to contact support is via the support wizard located here:, the wizard can lead you to email support for all issues OR Chat support for certain issues. UPDATE: As of : As of October 2020 (Due to Covid-19) Phone, and Social support no long are accessible. Update: As of – Call has been reintroduced as a support option. 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